muir
Banned
- MBTI
- INFJ
http://www.healthsentinel.com/jooml...ients-toxic-legacy&catid=5:original&Itemid=24
there are numerous studies from the medical and scientific literature that clearly show thimerosal is not a safe substance. The following are a few excerpts from a number of scientific journals:
there are numerous studies from the medical and scientific literature that clearly show thimerosal is not a safe substance. The following are a few excerpts from a number of scientific journals:
1977 - Archives of Disease in Childhood
"Although thiomersal [thimerosal] is an ethyl mercury compound, it has similar toxicological properties to methyl mercury and in long-term neurological sequelae [a pathological condition resulting from a disease, injury, or other trauma] produced by the ingestion of either methyl or ethyl mercury-based fungicides and indistinguishable ... Since it is clear that treatment of exomphalos [an umbilical hernia at birth in which some abdominal organs push into the umbilical cord] by the application of alcoholic mercurial antiseptics can produce blood and tissue levels of mercury well above the threshold at which damage occurs in all other age groups, it is extremely unlikely that these infants escape neurological damage, which may be subtle. We therefore suggest that treated survivors should be examined neurologically and psychologically as a matter of urgency. Organic mercurial antiseptics should be heavily restricted or withdrawn from hospital use, as the fact that mercury readily permeates intact membranes and is highly toxic seems to have been forgotten. Equally effective and far less toxic broad-spectrum antifungal and antibacterial topical antiseptics are currently available."
2003 - Toxicological Sciences
"In clinical cases of accidental or intentional usage in high concentrations, thimerosal was administered in doses from 3 mg/kg to several hundred mg/kg. Such doses resulted in local necrosis [The death of living cells or tissues] at the application site and severe central nervous system and kidney injury ... In this paper we demonstrated that extending the time of incubation with thimerosal from 2 to 6 hours is associated with toxicity that was not seen after a shorter time of exposure. For this reason, further studies of lower concentrations and longer exposure times appear to be warranted. These results indicate that additional research is needed to fully delineate the dose- and time-dependent toxicity of thimerosal in sub-micro-molar concentrations and suggests that toxicity may occur at even lower doses than those utilized in these experiments, with longer times of exposure. Because mercury can be retained in body organs for months to years, the study of longer incubation times is warranted."
2003 - Archives of toxicology
"In conclusion, thimerosal induced strong effects in the cytochalasin B in vitro [outside the living organism] micronucleus test in human lymphocytes ... Since thimerosal was repeatedly shown to be genotoxic [damaging to DNA] in vitro and in vivo [inside the living organism], there is reason for concern about its widespread use."
2004 - Toxicology
"Both thimerosal and methylmercury increased the [Ca2+]i and oxidative stress in cerebellar granule cells. In rat cerebellar granule neurons, the increase in [Ca2+]i induces an increase in oxidative stress while the oxidative stress increases the [Ca2+]i. It is a possibility that uncontrolled and sustained elevation of [Ca2+]I increases the formation of reactive oxygen species that induce a further increase in [Ca2+]i. If so, such insults induced by thimerosal and methylmercury would lead to cell injury or death in brain neurons ... In can be concluded that the potency of thimerosal to induce cytotoxic [substances that are toxic to cells] action on brain neurons dissociated from 2-week-old rats under the in vitro conditions is similar to that of methylmercury."
2005 - NeuroToxicology
"In both cell lines, a progressive increase in cytotoxicity [decrease in viability] was observed when Thimerosal dose was progressively doubled from 2.5 μmol/L [micromoles per liter] to 5, 10, and 20 μmol/L. Viability was reduced more than 50% in both cell lines with exposure to 10 μmol/L Thimerosal and less than 10% of cells survived a dose of 20 μmol/L. Thimerosal induces oxidative stress and apoptosis [programmed cell death] by activating mitochondrial cell death pathways. A subsequent study using cultured human neuron and fibroblast cell lines similarly showed that low micromolar concentrations of Thimerosal induced DNA strand breaks, caspase-3 activation, membrane damage and cell death."
2007 - Journal of Toxicology and Environmental Health
"The high order of toxicity from Thimerosal and its ethylmercury breakdown product has been known and published for decades. Nonetheless, Thimerosal remains in the drug supply, especially in various vaccines manufactured both for the United States and globally. The ubiquitous and largely unchecked place of Thimerosal in pharmaceutical products, therefore, represents a medical crisis in the modern day. Reforms in the manufacture and the licensing of vaccines and other drugs, which should have been accomplished proactively, had anyone properly assessed their mercury content, must now be conducted, reactively, under significant systemic stress. With no warning, recall, or ban of mercury in vaccines and other drugs as of yet, the victim of this mandated, unwarranted, and massive mercury exposure is still an unsuspecting public, and most especially its unborn and newborn children."
2007 - Anales de la Facultad de Medicina
"Due to the vast gaps in knowledge of thimerosal's pharmacokinetics and pharmacodynamics, as its toxic properties over the immune system, it is required to make more studies of quantitative character in animal models as soon as possible. Nevertheless, while it is true, it is difficult to extrapolate these findings to other animal experimentation groups and over human beings, our results, as the multiple scientific evidence recently published about thimerosal, clearly indicates the toxic nature of this substance, at the same dose and the same chronology as human immunizations; therefore we suggest the employment of alternative preservatives in vaccines, especially those intended to pregnant women, neonates, and small children based in the prevention and precaution principles of all medical interventions."
2008 - Neuroendocrinology Letters
"Thimerosal has been recognized by the California Environmental Protection Agency, Office of Environmental Health Hazard Assessment as a developmental toxin. This implies that Thimerosal may produce birth defects, low birth weight, biological dysfunctions, or psychological or behavior deficits that become manifest as the child grows. Maternal exposure during pregnancy may disrupt the development or even cause the death of the fetus. ... It is clear from these data that additional ND research should be undertaken in the context of evaluating mercury-associated exposures, especially from Thimerosal containing Rho(D)-immune globulins administered during pregnancy. Further studies should also be undertaken in additional databases/registries to assess the compatibility of the present results with trends in NDs in other US populations, and to observe whether Thimerosal-containing Rho(D)-immune globulins were associated with other birth defects in children. ... CONCLUSION: This study associates TCR [Thimerosal (49.55% mercury by weight) - containing Rho(D) immune globulins] exposure with some NDs [neurodevelopmental disorders] in children."
2008 - International Journal of Risk & Safety in Medicine
"Biological findings in autism that are consistent with mercury poisoning include elevated oxidative stress, depleted levels of glutathione, neurochemical irregularities, gastro-intestinal distress, immune dysregulation and generalized and neural inflammation. All of these are also well documented effects of
mercury poisoning and, specifically, mercury poisoning in infants ... Autism is a modern disease. It was first identified in the late 1930s and reported in 1943 by Kanner. It is important to place the arrival and subsequent epidemic growth of autism into the historical context of environmental exposure to mercury. Therefore, it is important to acknowledge that the commencement of widely available vaccinations (containing mercury) commenced in the 1930s. Additionally, the early 1900s saw the increasing availability and popularity of dental care where mercury amalgam fillings were the dominant restorative material ... The existing scientific literature provides grounds for strong suspicion that mercury plays a causal role in the development of autism. Given this suspicion, and the severe nature, devastating lifelong impact and extremely high prevalence of autism, it would be negligent to continue to expose pregnant and nursing mothers and infant children to any amount of avoidable mercury. Health authorities worldwide should move without hesitation to ban and remove all mercury in all medical products at the earliest possible date."
mercury poisoning and, specifically, mercury poisoning in infants ... Autism is a modern disease. It was first identified in the late 1930s and reported in 1943 by Kanner. It is important to place the arrival and subsequent epidemic growth of autism into the historical context of environmental exposure to mercury. Therefore, it is important to acknowledge that the commencement of widely available vaccinations (containing mercury) commenced in the 1930s. Additionally, the early 1900s saw the increasing availability and popularity of dental care where mercury amalgam fillings were the dominant restorative material ... The existing scientific literature provides grounds for strong suspicion that mercury plays a causal role in the development of autism. Given this suspicion, and the severe nature, devastating lifelong impact and extremely high prevalence of autism, it would be negligent to continue to expose pregnant and nursing mothers and infant children to any amount of avoidable mercury. Health authorities worldwide should move without hesitation to ban and remove all mercury in all medical products at the earliest possible date."
2009 - Behavioral and Brain Functions
"A disruption of the GSH (glutathione) system by mercury leads to GSH depletion and cell destruction. An in vitro study of Jurkat T cells exposed to thimerosal demonstrated concentration-dependent apoptosis. It was found that the mercury moiety [part of the molecule], not the thiosalicylic acid moiety, of thimerosal was responsible for glutathione depletion. GSH depletion is linked to several neurodegenerative disorders."
2009 - NeuroToxicology
Our study design does not enable us to determine whether it is the vaccine per se, the exposure to Th [thimerosal], or a combination of both that is causing the observed effects. None-the-less, the developing brain is considered the most vulnerable organ to mercury exposure, and experimental studies suggest that the brainstem - whose function is central to the reflexes described herein - may be one of the more sensitive targets ... Since the acquisition of motor reflexes is controlled by the brainstem, it is possible that very early exposure to ethyl mercury may adversely affect the emerging brainstem function ... this study provides preliminary evidence of abnormal early neurodevelopmental responses in male infant rhesus macaques [type of monkey] receiving a single dose of Th-containing [Thimerosal containing] HB [Hepatitis B] vaccine at birth and indicates that further investigation is merited."
There are still more studies not included in this article simply because the volume of information would be overwhelming, but the Material Data Safety Sheets and these scientific excerpts speak for themselves - Thimerosal is clearly a dangerous substance.
What the authors of that 1948 study probably didn't know when they said "If avoidance of the inconvenience of the average attack of pertussis is all that is expected" was that the historical data shows the death rate from pertussis had already fallen by 99% by the time they were writing their article and that their call to "diminish the hazard" of the vaccine would be apparently largely unheeded.
Sources:
Randolph K. Byers, M.D. and Frederic C. Moll, M.D., Encephalopathies Following Prophylactic Pertussis Vaccine, Pediatrics, April 1948, Vol. 1, No. 4, pp. 437-456
FDA website Thimerosal in Vaccines: http://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/VaccineSafety/ucm096228.htm
Thimerosal Material Safety Data Sheet - http://www.sciencelab.com/xMSDS-Thimerosal-9925236
Thimerosal Material Safety Data Sheet - Elli Lilly and Company, 22-Dec-1999
Fagan DG, Pritchard JS, Clarkson TW, Greenwood MR., Organ mercury levels in infants with omphaloceles treated with organic mercurial antiseptic. Archives of Disease in Childhood. 1977 Dec;52(12):962-4.
David S. Bakin, Hop Ngo, and Vladimir V. Didenko, Thimerosal Induced DNA Breaks, Caspase-3 Activation, Membrane Damage, and Cell Death in Cultured Human Neurons and Fibroblasts, Toxicological Sciences, Aug 2003, pp. 361-8.
WESTPHAL Götz A.; ASGARI Soha; SCHULZ Thomas G.; BÜNGER Jürgen; MÜLLER Michael; HALLIER Ernst; Thimerosal induces micronuclei in the cytochalasin B block micronucleus test with human lymphocytes, Archives of toxicology, 2003, vol. 77, no1, pp. 50-55
Toshiko Ueha-Ishibashi, Yasuo Oyama, Hiromi Nakao, Chisato Umebayashi, Yasutaka Nishizaki, Tomoko Tatsuishi, Kyoko Iwase, Koji Murao and Hakaru Seo, Effect of thimerosal, a preservative in vaccines, on intracellular Ca2+ concentration of rat cerebellar neurons, Toxicology, Volume 195, Issue 1, 15 January 2004, Pages 77-84
S.J. James, William Slikker III, Stepan Melnyk, Elizabeth New, Marta Pogribna, Stefanie Jernigan, Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors, NeuroToxicology, Vol. 26, 2005, pp. 1-8
David A. Geier, Lisa K. Sykes, Mark R. Geier, A REVIEW OF THIMEROSAL (MERTHIOLATE) AND ITS ETHYLMERCURY BREAKDOWN PRODUCT: SPECIFIC HISTORICAL CONSIDERATIONS REGARDING SAFETY AND EFFECTIVENESS, Journal of Toxicology and Environmental Health, Part B, 10:575-596, 2007
Jonny Laurente, Fany Remuzgo, Betthina Ãvalos, Johnnie Chiquinta, Bladimir Ponce, Ronald Avendaño, Luis Maya, Neurotoxic effects of thimerosal at vaccine doses on the encephalon and development in 7 day-old hamsters, Anales de la Facultad de Medicina, 2007; 68(3), pp. 222-237
David A. Geier, Elizabeth Mumper, Bambi Gladfelter, Lisa Coleman, and Mark R. Geier, Neurodevelopmental Disorders, Maternal Rh-Negativity, and Rho(D) Immune Globulins: A Multi-Center Assessment, Neuroendocrinology Letters, Volume 29, No. 2 2008
David Austin, An epidemiological analysis of the ‘autism as mercury poisoning' hypothesis, International Journal of Risk & Safety in Medicine, 20 (2008) pp. 135-142
Renee Dufault, Roseanne Schnoll, Walter J Lukiw, Blaise LeBlanc, Charles Cornett, Lyn Patrick, David Wallinga, Steven G Gilbert and Raquel Crider, Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children, Behavioral and Brain Functions, 2009, 5:44
Laura Hewitson, Lisa A. Housera, Carol Stottc, Gene Sackett, Jaime L. Tomko, David Atwood, Lisa Blue, E. Railey Whited and Andrew J. Wakefield, Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight, NeuroToxicology, October 2009